Exacerbations are frightening events resulting in increased patient anxiety, worsening health status, lung function decline and increased risk of death.
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The lung function improvements on top of current bronchodilation clearly indicates that roflumilast improves lung function over and above what can be achieved with other COPD treatments alone.
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The results of the two six-month trials examining the additive effect of roflumilast on top of salmeterol or tiotropium support and extend the findings of the 12-month trials, by showing a clinically relevant lung function improvement in patients with im
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