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Nausea, diarrhoea and weight loss were the most common adverse events recorded in patients in the four trials, but they were generally mild to moderate in intensity and generally occurred in the first weeks of treatment.
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The studies showed a reduction in moderate to severe exacerbations by 17 percent per patient per year (rate of 1.
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Use Januvia as directed by your doctor. Check the label on the medicine for exact dosing instructions.
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The reduction in exacerbations was irrespective of concomitant treatment with long-acting beta-2 agonists, a standard bronchodilator therapy.